1-Acetyl-4-(4-hydroxyphenyl)piperazine

CAS: 67914-60-7

Ref. 3D-FA17079

Product Information

• Name: 1-Acetyl-4-(4-hydroxyphenyl)piperazine
• Synonyms: 1-[4-(4-Hydroxyphenyl)-1-piperazinyl]ethanone4-(4-Acetylpiperazino)phenol1-Acetyl-4-(p-hydroxyphenyl)piperazine, 1-Acetyl-4-(4hydroxyphenyl)piperazine, 1-Acetyl-4-(p-hydroxyphenyl)piperazine, 1-[4-(4-Hydroxyphenyl)-1-piperazinyl]ethanone, 1-[4-(4-Hydroxyphenyl)Piperazin-1-Yl]Ethanone, 1-[4-(4-Hydroxyphenyl)piperazin-1-yl]ethan-1-one, 4-(1-Acetylpiperazin-4-yl)phenol, 4-(4-Acetyl-1-piperazino)phenol, 4-(4-Acetylpiperazin-1-yl)phenol, 4-(4-Acetylpiperazin-4-Yl)Phenol, 4-(4-Acetylpiperazino)phenol, Ethanone, 1-[4-(4-hydroxyphenyl)-1-piperazinyl]-, Piperazine, 1-acetyl-4-(4-hydroxyphenyl)-, T 1141, Tetraethoxy C methyl propane
• CAS: 67914-60-7

Description

1-Acetyl-4-(4-hydroxyphenyl)piperazine is a triazole antifungal that inhibits the synthesis and activity of nitric oxide. It binds to the N1 atom of the molecule, which is the site of nitrite ion, and prevents it from reacting with chloride ions. This binding also prevents nucleophilic attack on imine bonds in proteins and DNA. The photophysical properties of 1-acetyl-4-(4-hydroxyphenyl)piperazine are determined by its coumarin derivatives, which absorb light at wavelengths between 400 and 500 nm. The compound has been found to be specific for fungi, but not bacteria or yeast.
1-Acetyl-4-(4-hydroxyphenyl)piperazine has been shown to be effective against Candida albicans and other strains of yeast when used as an oral or topical treatment.

• Brand: Biosynth

Chemical properties

• Molecular weight: 220.27 g/mol
• Formula: C₁₂H₁₆N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C12H16N2O2/c1-10(15)13-6-8-14(9-7-13)11-2-4-12(16)5-3-11/h2-5,16H,6-9H2,1H3
• InChI key: InChIKey=AGVNLFCRZULMKK-UHFFFAOYSA-N
• SMILES: CC(=O)N1CCN(c2ccc(O)cc2)CC1