N-Acetyl-4-aminosalicylic acid

CAS: 50-86-2

Ref. 3D-FA17083

Product Information

• Name: N-Acetyl-4-aminosalicylic acid
• Synonyms: 4-Acetylamino-2-hydroxybenzoic acid4-Acetamidosalicylic acidp-Acetamidosalicylic acid, 2-Hydroxy-4-acetamidobenzoic acid, 3-Hydroxy-4-carboxyacetanilide, 4-(Acetylamino)-2-hydroxybenzoic acid, 4-Acetamido-2-hydroxybenzoic acid, 4-Acetamidosalicylic acid, 4-Acetaminosalicylic acid, 4-Azetaminosalizylsaeure, 4-Azetaminosalizylsaeure [German], Acide 4-acetaminosalicylique, Acide 4-acetaminosalicylique [French], Benzoic acid, 4-(acetylamino)-2-hydroxy-, Benzoic acid, 4-(acetylamino)-2-hydroxy- (9CI), Benzoic acid, 4-acetamido-2-hydroxy-, Brn 0395899, N-Acetyl-4-aminosalicyclic acid, N-Acetyl-p-aminosalicylic acid, N-Acetyl-pas, Nsc 54182, Salicylic acid, 4-acetamido-, Ws 176, p-(Acetylamino)salicylic acid, p-Acetamidosalicylic acid, 4-14-00-02020 (Beilstein Handbook Reference)

Description

N-Acetyl-4-aminosalicylic acid is an active site directed probe for the detection of salicylic acid. It has a fluorescence emission maximum at 370 nm and a fluorescence quantum yield of 0.93. N-Acetyl-4-aminosalicylic acid can be used to analyze samples, such as wastewater and human urine, which contain salicylic acid. The probe is protonated in the presence of salicylic acid and then binds to the acceptor in the sample with a bimodal distribution. The fluorescence resonance energy transfer (FRET) process between the donor and acceptor leads to an increase in fluorescence intensity that can be detected by electrophoresis methods. This probe also has a conformational change when it binds to its target, which allows for easy separation from other components in the sample by size exclusion chromatography.

• Brand: Biosynth

Chemical properties

• Molecular weight: 195.17 g/mol
• Formula: C₉H₉NO₄
• Purity: Min. 95%
• Color/Form: Slightly Brown Powder
• InChI: InChI=1S/C9H9NO4/c1-5(11)10-6-2-3-7(9(13)14)8(12)4-6/h2-4,12H,1H3,(H,10,11)(H,13,14)
• InChI key: InChIKey=YBTVSGCNBZPRBD-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1ccc(C(=O)O)c(O)c1