N-γ-Acetyl-N-2-formyl-5-methoxykynurenamine
CAS: 52450-38-1
Ref. 3D-FA17136
| 1mg | Discontinued | ||
| 2mg | Discontinued | ||
| 5mg | Discontinued | ||
| 10mg | Discontinued | ||
| 25mg | Discontinued |
Product Information
Name:
N-γ-Acetyl-N-2-formyl-5-methoxykynurenamine
Synonyms:
- N-[3-[2-(Formylamino)-5-methoxyphenyl]-3-oxopropyl]acetamideN1-Acetyl-N2-formyl-5-methoxykynuramineNSC 688263
- AFMK
- N-[3-[2-(Formylamino)-5-methoxyphenyl]-3-oxopropyl]acetamide
- Acetamide, N-[3-[2-(formylamino)-5-methoxyphenyl]-3-oxopropyl]-
- N1-Acetyl-N2-formyl-5-methoxykynuramine
- NSC 688263
Description:
N-gamma-Acetyl-N-2-formyl-5-methoxykynurenamine is a reactive metabolite that is produced by the enzyme tryptophan 2,3 dioxygenase (TDO). This compound has been shown to be a potent inducer of oxidative injury and neuronal death in vivo in humans. It targets enzymes involved in energy metabolism, such as mitochondrial membrane potential and polymerase chain reaction. N-gamma-Acetyl-N-2-formyl-5-methoxykynurenamine has been shown to cause oxidative stress in a model system. This reactive metabolite can also act as a fluorescence probe for melatonin or transfer reactions with other compounds to form fluorescent species.
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
264.28 g/mol
Formula:
C13H16N2O4
Purity:
Min. 95%
Color/Form:
Beige Powder
InChI:
InChI=1S/C13H16N2O4/c1-9(17)14-6-5-13(18)11-7-10(19-2)3-4-12(11)15-8-16/h3-4,7-8H,5-6H2,1-2H3,(H,14,17)(H,15,16)
InChI key:
InChIKey=JYWNYMJKURVPFH-UHFFFAOYSA-N
SMILES:
COc1ccc(NC=O)c(C(=O)CCNC(C)=O)c1
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