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4-Amino-1-tert-butyl-3-(2-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine
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4-Amino-1-tert-butyl-3-(2-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine

CAS: 1027572-46-8

Ref. 3D-FA17423

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Estimated delivery in United States, on Tuesday 7 Jan 2025

Product Information

Name:
4-Amino-1-tert-butyl-3-(2-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine
Synonyms:
  • Hydroxy-PP
Description:

4-Amino-1-tert-butyl-3-(2-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine (ABT) is a new anticancer drug that inhibits the growth of prostate cancer cells. ABT binds to response elements in the promoter region of genes, blocking transcription and causing cancer cells to undergo apoptosis. This compound has also been shown to inhibit the proliferation of human liver cells. The cytotoxic effects of ABT were investigated using cellular physiology and molecular modeling studies. ABT showed strong cytotoxicity against a number of human cancer cell lines, including breast, leukemia, colon, lung and prostate cancers. It also inhibited the growth of animal models for congestive heart failure. The IC50 values for these compounds are in the low micromolar range with MTT assay data suggesting that ABT is more potent than erythromycin A.
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Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
283.33 g/mol
Formula:
C15H17N5O
Purity:
Min. 95%
InChI:
InChI=1S/C15H17N5O/c1-15(2,3)20-14-11(13(16)17-8-18-14)12(19-20)9-6-4-5-7-10(9)21/h4-8,21H,1-3H3,(H2,16,17,18)
InChI key:
InChIKey=CPZBAYHPGAUAKO-UHFFFAOYSA-N
SMILES:
CC(C)(C)n1nc(-c2ccccc2O)c2c(N)ncnc21
MDL:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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