2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane

CAS: 144164-11-4

Ref. 3D-FA17438

Product Information

• Name: 2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane
• Synonyms: 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate, 1,3-thiazol-5-ylmethyl [(1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate, 2S,3S,5S-5-Amino-2-[N-[[(5-Thiazolyl)Methoxy]Carbonyl]Amino]-1,6-Diphenyl-3-Hydroxyhexane, Carbamic acid, N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 5-thiazolylmethyl ester, Carbamic acid, [(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 5-thiazolylmethyl ester, Carbamic acid, [4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 5-thiazolylmethyl ester, [1S-(1R*,2R*,4R*)]-, Rt-10, thiazol-5-ylmethyl (2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-ylcarbamate

Description

2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane is a pharmaceutical intermediate that is used in the synthesis of ritonavir. It can be prepared with an efficiency of up to 98% and has a reaction time of less than one hour. The compound can be manufactured using industrial solvents such as nitrogen or organic solvents such as benzene. 2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane is typically made by the reaction of alkali with an organic acid chloride. This process generates byproducts that are then removed from the product by

• Brand: Biosynth

Chemical properties

• Molecular weight: 425.54 g/mol
• Formula: C₂₃H₂₇N₃O₃S
• Purity: Min. 95%
• InChI: InChI=1S/C23H27N3O3S/c24-19(11-17-7-3-1-4-8-17)13-22(27)21(12-18-9-5-2-6-10-18)26-23(28)29-15-20-14-25-16-30-20/h1-10,14,16,19,21-22,27H,11-13,15,24H2,(H,26,28)/t19-,21-,22-/m0/s1
• InChI key: InChIKey=HBPTXDXGWDVDON-BVSLBCMMSA-N
• SMILES: N[C@@H](Cc1ccccc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1cncs1