4-(Aminomethyl)phenylboronic acid

CAS: 51239-46-4

Ref. 3D-FA175649

Product Information

• Name: 4-(Aminomethyl)phenylboronic acid

Description

4-(Aminomethyl)phenylboronic acid (4-ABA) is an inhibitor of the enzyme creatine kinase. It is a potent inhibitor of inflammatory diseases and has been shown to be effective in treating autoimmune diseases and cancer. 4-ABA binds to the copper complex of the enzyme, inhibiting ATP synthesis by phosphorylation of ADP. This inhibition leads to cell death through hypoxic tumor growth or other mechanisms. 4-ABA also has a potent inhibitory activity against human creatinine kinase, which may be due to its ability to form a stable electrochemical complex with nucleophilic sites on the enzyme.

• Brand: Biosynth

Chemical properties

• Molecular weight: 150.97 g/mol
• Formula: C₇H₁₀BNO₂
• Purity: Min. 95%
• InChI: InChI=1S/C7H10BNO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4,10-11H,5,9H2
• InChI key: InChIKey=KMWLUGSVWULTHR-UHFFFAOYSA-N
• SMILES: NCc1ccc(B(O)O)cc1