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2-Amino-4-chloro-5-nitropyridine
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2-Amino-4-chloro-5-nitropyridine

CAS: 24484-96-6

Ref. 3D-FA17567

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Estimated delivery in United States, on Tuesday 7 Jan 2025

Product Information

Name:
2-Amino-4-chloro-5-nitropyridine
Synonyms:
  • 4-Chloro-5-nitro-2-pyridinamine4-Chloro-5-nitropyridine-2-amine
  • 2-Amino-4-Chloro-5-Nitropyridine
  • 4-Chloro-5-nitropyridin-2-amine
Description:

2-Amino-4-chloro-5-nitropyridine is an amino function that inhibits the enzyme transcriptase. 2-Amino-4-chloro-5-nitropyridine is a competitive inhibitor of HIV reverse transcriptase and can be used to treat HIV infections. The ethyl esters of 2-amino-4, 5 nitropyridines are also potent inhibitors of human immunodeficiency virus type 1 (HIV) and have been shown to inhibit malonate degradation in the presence of wild type and mutant HIV enzymes. This inhibition was found to be due to the inhibition of the 3'-end processing by transcriptase. These compounds were shown to bind reversibly with high affinity at the active site of RNA polymerase II, which may lead to enhanced binding affinity for nucleic acid substrates. Molecular modeling studies suggest that these compounds would be better inhibitors if they were diethyl esters rather than ethyl esters

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
173.56 g/mol
Formula:
C5H4ClN3O2
Purity:
Min. 95%
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Hazard Info

UN Number:
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Forbidden to fly:
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LQ:

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