3-Amino-4-(2,4,5-trifluorophenyl)butyric acid

CAS: 1283583-85-6

Ref. 3D-FA175801

Product Information

• Name: 3-Amino-4-(2,4,5-trifluorophenyl)butyric acid

Description

3-Amino-4-(2,4,5-trifluorophenyl)butyric acid is a 6-membered ring with an azide group and a nitrogen atom. It is an inhibitor of dipeptidyl peptidase IV (DPPIV), which is involved in the breakdown of proteins. 3-Amino-4-(2,4,5-trifluorophenyl)butyric acid binds to the active site of DPPIV and blocks its access to the substrate. This inhibition causes an increase in blood levels of amino acids such as proline and hydroxyproline. The reaction scheme for this compound is shown below: The synthesis starts with the Grignard reaction between 2,4,5-trifluoroaniline and ethylmagnesium bromide in diethylether at 0°C. The resulting Grignard reagent reacts with aziridine to produce

• Brand: Biosynth

Chemical properties

• Molecular weight: 233.19 g/mol
• Formula: C₁₀H₁₀F₃NO₂
• Purity: Min. 95%
• Color/Form: White Off-White Powder
• InChI: InChI=1S/C10H10F3NO2/c11-7-4-9(13)8(12)2-5(7)1-6(14)3-10(15)16/h2,4,6H,1,3,14H2,(H,15,16)
• InChI key: InChIKey=KEFQQJVYCWLKPL-UHFFFAOYSA-N
• SMILES: NC(CC(=O)O)Cc1cc(F)c(F)cc1F