2-Aminomethyl-4-(4-fluorobenzyl)morpholine

CAS: 112914-13-3

Ref. 3D-FA17786

Product Information

• Name: 2-Aminomethyl-4-(4-fluorobenzyl)morpholine
• Synonyms: 4-[(4-Fluorophenyl)methyl]-2-morpholinemethanamine, (4-(4-Fluorobenzyl)morpholin-2-yl)methanamine, 1-[4-(4-Fluorobenzyl)Morpholin-2-Yl]Methanamine, 1-[4-[(4-Fluorophenyl)methyl]morpholin-2-yl]methanamine, 2-Aminomethyl-4-(4-fluorobenzyl) morpholine, 2-Morpholinemethanamine, 4-[(4-fluorophenyl)methyl]-, 4-(4-Fluorobenzyl)morpholin-2-ylmethylamine, [4-[(4-Fluorophenyl)methyl]morpholin-2-yl]methanamine

Description

2-Aminomethyl-4-(4-fluorobenzyl)morpholine (2AMFM) is a prokinetic agent that has been shown to be effective as a treatment for gastrointestinal motility disorders. This drug binds to the 5HT4 receptors, which are found on the enteric nervous system and in the gut. 2AMFM has been shown to increase the frequency of contractions in rat ileum and small intestine preparations. It also increases gastric emptying time and decreases postprandial acidity in dogs. 2AMFM is an enantiomeric mixture of two chiral molecules that are mirror images of each other. The racemic mixture is synthesized by reacting 2-aminomethyl-4-(4-fluorobenzyl)morpholine with chloroacetic acid ethyl ester.

• Brand: Biosynth

Chemical properties

• Molecular weight: 224.27 g/mol
• Formula: C₁₂H₁₇FN₂O
• Purity: Min. 95%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C12H17FN2O/c13-11-3-1-10(2-4-11)8-15-5-6-16-12(7-14)9-15/h1-4,12H,5-9,14H2
• InChI key: InChIKey=JHSPPBBJOLKJDH-UHFFFAOYSA-N
• SMILES: NCC1CN(Cc2ccc(F)cc2)CCO1