5-Aminothiazolo[4,5-d]pyrimidine-2,7(3H,6H)-dione

CAS: 30161-97-8

Ref. 3D-FA17863

Product Information

• Name: 5-Aminothiazolo[4,5-d]pyrimidine-2,7(3H,6H)-dione
• Synonyms: 5-Amino-thiazolo[4,5-d]pyrimidine-2,7-diol

Description

Ganciclovir is an antiviral drug that inhibits the synthesis of DNA, which is required for viral replication. It is effective against a number of viruses, including cytomegalovirus and herpesviruses. Ganciclovir binds to the enzyme thymidine kinase, which converts ganciclovir into the active form, 5-amino-2',3'-dideoxycytidine triphosphate (5-ADCTP). This active form prevents DNA synthesis by inhibiting the function of DNA polymerase. Ganciclovir also has in vitro antiviral activity against murine leukemia virus type II (MLV-II) and human immunodeficiency virus type 1 (HIV-1). The drug is not active against human T cell lymphotrophic virus type I (HTLV-I), influenza A virus type A/PR/8/34 (PR8), or influenza B virus type B/Brisbane/

• Brand: Biosynth

Chemical properties

• Molecular weight: 184.18 g/mol
• Formula: C₅H₄N₄O₂S
• Purity: Min. 95%
• InChI: InChI=1S/C5H4N4O2S/c6-4-7-2-1(3(10)9-4)12-5(11)8-2/h(H4,6,7,8,9,10,11)
• InChI key: InChIKey=YDWRPBIUDIYAOX-UHFFFAOYSA-N
• SMILES: Nc1nc2[nH]c(=O)sc2c(=O)[nH]1