Apicidin
CAS: 183506-66-3
Ref. 3D-FA17952
| 1mg | To inquire | ||
| 2mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire |
Product Information
- Cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl]Cyclo(8-oxo-L-2-aminodecanoyl-1-metho xy-L-tryptophyl-L-isoleucyl-D-2-piperidinecarbonyl)Apicidin ia
- Cyclo-L-(2-Amino-8-Oxodeacanoyl)-L-(N-Methoxy-Tryptophan)-L-Isoleucyl-D-Pipecolinyl
- Cyclo-[L-(2-Amino-8-Oxodecanoyl)-L-(N-Methoxytryptophan)-L-Isoleucyl-D-Pipecolinyl
- Cyclo[(2S)-2-Amino-8-Oxodecanoyl-1-Methoxy-L-Tryptophyl-L-Isoleucyl-(2R)-2-Piperidinexcarbonyl]
- Apicidin, Fusarium Species
- (3S,6S,9S,15aR)-6-[(1-methoxy-1H-indol-3-yl)methyl]-9-[(1S)-1-methylpropyl]-3-(6-oxooctyl)octahydro-2H-pyrido[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10(3H,12H)-tetrone
Apicidin is a cyclic peptide that is structurally similar to the natural antibiotic apigenin. It has been shown to inhibit cancer cell proliferation and induce apoptosis in vitro. Apicidin has also been shown to be effective against squamous carcinoma, hl-60 cells, and mitochondrial membrane potential, as well as other types of cancer cells in vivo. Apicidin binds to the mitochondrial membrane and inhibits ATP synthesis by blocking the electron transport chain. This causes a decrease in cellular energy production and an increase in intracellular oxidative stress which leads to apoptosis.
Chemical properties
Technical inquiry about: 3D-FA17952 Apicidin
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
