7-Azagramine

CAS: 5654-92-2

Ref. 3D-FA18056

Product Information

• Name: 7-Azagramine
• Synonyms: N,N-Dimethyl-1H-pyrrolo[2,3-b]pyridine-3-methanamine3-(Dimethylaminomethyl)-7-azaindole3-[(Dimethylamino)methyl]-1H-pyrrolo[2,3-b] pyridine, 1H-pyrrolo[2,3-b]pyridine-3-methanamine, α,α-dimethyl-, 3-(Dimethylaminomethyl)-7-azaindole

Description

7-Azagramine is a structural modification of the morpholine molecule that has been synthesised and tested for its affinity to dopamine D4 and D2 receptors. The modifications of 7-azagramine are based on the pharmacophore of the original compound, which is an amine group connected to two heterocyclic rings. The affinity of 7-azagramine for the D4 receptor was found to be significantly greater than that for D2. This suggests that 7-azagramine may be a useful drug for treating schizophrenia, Parkinson’s disease, and other neurological disorders.

• Brand: Biosynth

Chemical properties

• Molecular weight: 175.23 g/mol
• Formula: C₁₀H₁₃N₃
• Purity: Min. 95%
• InChI: InChI=1S/C10H13N3/c1-13(2)7-8-6-12-10-9(8)4-3-5-11-10/h3-6H,7H2,1-2H3,(H,11,12)
• InChI key: InChIKey=RFLCFQLBXWLHKX-UHFFFAOYSA-N
• SMILES: CN(C)Cc1c[nH]c2ncccc12