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6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one
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6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one

CAS: 56287-74-2

Ref. 3D-FA29178

1g
714.00 €
50mg
113.00 €
100mg
183.00 €
250mg
382.00 €
500mg
510.00 €
Estimated delivery in United States, on Friday 24 May 2024

Product Information

Name:
6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one
Controlled Product
Synonyms:
  • Afloqualone
  • (2-Tolyl)-3H-quinazolin-4-one
  • 4(3H)-quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-
  • 6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone
  • 6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4(3H)-one
  • 6-Amino-2-Fluoromethyl-3-
  • Aroft
  • Arofuto
  • H 495
  • Hq 495
  • See more synonyms
Description:

6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one is a potent inhibitor of the enzyme dihydrofolate reductase, which is required for the synthesis of DNA and other macromolecules. It has been shown to inhibit the growth of cutaneous lesions in mice and rats. The compound has also been found to be effective against renal lesions (caused by cevimeline hydrochloride) in rats. The compound has a high inhibitory dose as it binds tightly with divalent metal ions such as magnesium, calcium, and zinc. This property may result in its use as an anticancer drug.
6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one is soluble in water and polymeric matrices and can be administered orally or intravenously.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
283.3 g/mol
Formula:
C16H14FN3O
Purity:
Min. 95%
Color/Form:
White Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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