4-Aminobenzoic acid potassium salt

CAS: 138-84-1

Ref. 3D-FA29212

Product Information

• Name: 4-Aminobenzoic acid potassium salt
• Synonyms: PABA, 4-Aminobenzoate potassium salt, 4-Aminobenzoic acid potassium, Aminobenzoate potassium, Benzoic acid, 4-amino-, monopotassium salt, Benzoic acid, 4-amino-, potassium salt (1:1), Benzoic acid, p-amino-, monopotassium salt, Kpaba, P-Aminobenzoic Acid Potassium Salt, Potaba, Potassium 4-Aminobenzoate, Potassium p-amino-benzoate, Potassium p-aminobenzoate, Potoba

Description

4-Aminobenzoic acid potassium salt (4ABAP) is a skin cancer treatment that belongs to the group of pyrazinoic acid derivatives. It inhibits the polymerase chain reaction and prevents DNA replication by binding to the magnesium ion in an enzyme called pyrazinamidase. 4ABAP has been shown to have promising activity against wild-type strains, such as Aerobacter aerogenes and Streptococcus pneumoniae, but not against human pathogens such as Escherichia coli. The structural analysis of 4ABAP showed that it is a competitive inhibitor of phenylalanine hydroxylase, which is an enzyme that converts p-hydroxybenzoic acid into benzoic acid. 4ABAP binds to the active site of phenylalanine hydroxylase by chelating with magnesium ions and inhibiting the conversion process, leading to cell death by depletion of p-hydroxybenzoic acid.

• Brand: Biosynth

Chemical properties

• Molecular weight: 175.23 g/mol
• Formula: C₇H₆KNO₂
• Purity: Min. 95%
• Color/Form: Solid