AEBSF hydrochloride

CAS: 30827-99-7

Ref. 3D-FA29609

Product Information

• Name: AEBSF hydrochloride
• Synonyms: 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, (2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 2,4,6-Tribromo-3,5-Difluoropyridine, 2-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride, 2-[4-(Fluorosulfonyl)phenyl]ethanaminium chloride, 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride (1:1), 4-(2-Aminoethyl)benzenesulfonylfluoride hydrochloride, Aebsf, Benzenesulfonyl fluoride, 4-(2-aminoethyl)-, hydrochloride, Benzenesulfonyl fluoride, 4-(2-aminoethyl)-, hydrochloride (1:1), Benzenesulfonyl fluoride, p-(2-aminoethyl)-, hydrochloride, Pefabloc, Pefabloc SC, Pefabloc SC Plus
• CAS: 30827-99-7

Description

4-(2-Aminoethyl)-benzenesulfonylfluoride hydrochloride, also known as AEBSF, is an irreversible serine protease inhibitor. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. It inhibits by acylation of the activesite of the enzyme. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0.25 mM. Aqueous solutions are stable between pH 5-6; limited stability above pH 7.5.

• Brand: Biosynth

Chemical properties

• Molecular weight: 239.7 g/mol
• Formula: C₈H₁₀FNO₂S·HCl
• Purity: Min. 98 Area-%
• Color/Form: White Powder