a-Methyl cinnamic acid

CAS: 1199-77-5

Ref. 3D-FA30853

Product Information

• Name: a-Methyl cinnamic acid
• Synonyms: (2E)-2-methyl-3-phenylprop-2-enoate, (2E)-2-methyl-3-phenylprop-2-enoic acid, (2Z)-2-methyl-3-phenylprop-2-enoic acid, 2-Methyl-3-Phenylprop-2-Enoic Acid, 2-Methyl-3-phenyl-2-propenoic acid, 2-Methyl-3-phenylacrylicacid, 2-Propenoic acid, 2-methyl-3-phenyl-, 3-Phenyl-2-methyl-2-propenoic acid, Cinnamic acid, α-methyl-, NSC 401113, α-Methylcinnamic acid

Description

a-Methyl cinnamic acid is a synthetic compound that is used in the synthesis of drugs for the treatment of cancer. It can be produced by Friedel-Crafts reaction between chloroform, benzaldehyde, and morpholine. The product is recycled as a raw material for production of amide derivatives. The reaction yield is not high and requires large amounts of chloroform and morpholine. In addition to carcinogenic compounds, a-methyl cinnamic acid also contains chloride ions, which are toxic to the environment. Pressor activity has been observed in rats treated with intravenous a-methyl cinnamic acid. Cinchonidine has been shown to be able to inhibit the pressor effects of a-methyl cinnamic acid in rats.

• Brand: Biosynth

Chemical properties

• Molecular weight: 162.19 g/mol
• Formula: C₁₀H₁₀O₂
• Purity: Min. 95%
• InChI: InChI=1S/C10H10O2/c1-8(10(11)12)7-9-5-3-2-4-6-9/h2-7H,1H3,(H,11,12)/b8-7+
• InChI key: InChIKey=XNCRUNXWPDJHGV-BQYQJAHWSA-N
• SMILES: C/C(=C\c1ccccc1)C(=O)O