N-[(4-Amino-2-methylpyrimidin-5-yl)methyl]formamide

CAS: 1886-34-6

Ref. 3D-FA31702

Product Information

• Name: N-[(4-Amino-2-methylpyrimidin-5-yl)methyl]formamide
• Synonyms: 2-Methyl-4-amino-5-(formylaminomethyl)pyrimidine, 4-AMino-5-(forMaMidoMethyl)-2-MethylpyriMidine, 4-Amino-5-((formylamino)methyl)-2-methylpyrimidine, N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]formamide, S-((4-Amino-2-methylpyrimidin-5-yl)methyl) formamide, formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-

Description

N-[(4-Amino-2-methylpyrimidin-5-yl)methyl]formamide (NAMPT) is a triazolo compound that inhibits the ATP binding cassette transporter and blocks the uptake of uridine and pyrimidine compounds. It also inhibits inorganic pyrophosphatase, which is an enzyme that catalyzes the hydrolysis of pyrophosphate to inorganic phosphate. NAMPT has been shown to be a substrate for hypochlorous acid production in neutrophils, suggesting it may play a role in the regulation of oxidative stress. Chemical biology studies have demonstrated that NAMPT plays a physiological function as an intermediate in vitamin B1 biosynthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 166.18 g/mol
• Formula: C₇H₁₀N₄O
• Purity: Min. 95%
• Color/Form: Powder