1-(3-Aminophenyl)piperidine

CAS: 27969-75-1

Ref. 3D-FA33472

Product Information

• Name: 1-(3-Aminophenyl)piperidine
• Synonyms: 1-Amino-3-piperidinobenzene, 3-(1-Piperidino)aniline, 3-(1-Piperidinyl)benzenamine, 3-(Piperidin-1-yl)aniline, 3-(Piperidin-1-yl)phenylamine, Benzenamine, 3-(1-piperidinyl)-, N-(m-Aminophenyl)piperidine, Piperidine, 1-(m-aminophenyl)-, m-Piperidinoaniline

Description

1-(3-Aminophenyl)piperidine is a molecule that inhibits the transcription of mycobacterial genes. It is a hydrophobic molecule with four cavities, which are not symmetrical and are not found in any other known molecules. This makes it an interesting target for drug discovery because it has no structural similarities to any other known molecules. The molecule was discovered by screening for molecules that can inhibit the transcriptional activity of mycobacterium tuberculosis. 1- (3-aminophenyl) piperidine binds to the repressor protein, preventing its interaction with RNA polymerase, thus inhibiting transcription and replication of DNA. This molecule also boosts the activity of ethionamide, which is another drug used to treat tuberculosis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 176.26 g/mol
• Formula: C₁₁H₁₆N₂
• Purity: Min. 95%
• InChI: InChI=1S/C11H16N2/c12-10-5-4-6-11(9-10)13-7-2-1-3-8-13/h4-6,9H,1-3,7-8,12H2
• InChI key: InChIKey=HHPBFHJCBMETRO-UHFFFAOYSA-N
• SMILES: Nc1cccc(N2CCCCC2)c1