2-Amino-5-methyl-1,3,4-thiadiazole

CAS: 108-33-8

Ref. 3D-FA34351

Product Information

• Name: 2-Amino-5-methyl-1,3,4-thiadiazole
• Synonyms: 5-Methyl-1,3,4-thiadiazol-2-amine, (5-Methyl-1,3,4-thiadiazol-2-yl)amine, 1,3,4-Thiadiazol-2-amine, 5-methyl-, 1,3,4-Thiadiazole, 2-amino-5-methyl-, 2-Amino-5-methylthiadiazole, 2-Methyl-5-amino-1,3,4-thiadiazole, 3-methyl-1H-1,2,4-triazol-5-amine, 5-Amino-2-methyl-1,3,4-thiadiazole, 5-Methyl-1,3,4-thiadiazol-2-ylamine, 5-Methyl-1,3,4-thiadiazole-2-amine, 5-Methyl-2-amino-1,3,4-thiadiazole, NSC 137228, NSC 526661

Description

2-Amino-5-methyl-1,3,4-thiadiazole is an organic solvent that is used as a feedstock in the production of other organic compounds. 2-Amino-5-methyl-1,3,4-thiadiazole has been detected in drinking water and soil samples collected near industrial sites. The toxicity of 2-amino-5 methyl 1,3,4 thiadiazole to bacteria is related to its ability to interfere with cell respiration. When 2 aminothiadiazole enters the cell it reacts with the enzyme cytochrome oxidase which is essential for aerobic respiration. This reaction inhibits the electron transport chain that provides energy for ATP synthesis and DNA replication.
2 aminothiadiazole also inhibits nitrate reductase and glutathione reductase enzymes which are necessary for cellular detoxification processes.
The mechanism of toxicity for this chemical is due

• Brand: Biosynth

Chemical properties

• Molecular weight: 115.16 g/mol
• Formula: C₃H₅N₃S
• Purity: Min. 95%
• InChI: InChI=1S/C3H5N3S/c1-2-5-6-3(4)7-2/h1H3,(H2,4,6)
• InChI key: InChIKey=HMPUHXCGUHDVBI-UHFFFAOYSA-N
• SMILES: Cc1nnc(N)s1