6-Amino-6-deoxyluciferin

CAS: 118969-27-0

Ref. 3D-FA36330

Product Information

• Name: 6-Amino-6-deoxyluciferin
• Synonyms: ADL, 6-Amino-6-Deoxyluciferin, 6-Amino-D-Luciferin, 6-Amino Luciferin, 6-Amino-6-Deoxyluciferin (Adl), 2-(6-Amino-1,3-Benzothiazol-2-Yl)-4,5-Dihydro-1,3-Thiazole-4-Carboxylic Acid

Description

6-Amino-6-deoxyluciferin is a synthetic analog of luciferin. It is used as a substrate for bacterial luciferase and in immunoassays to detect neutrophils, infectious diseases, and various protease activities. 6-Amino-6-deoxyluciferin is synthesized by the condensation of an amide with a hydroxyl group from acetaldehyde. This reaction requires the use of a coupling agent such as dicyclohexylcarbodiimide or 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC), which are often used to form amides from carboxylic acids and amines. The conjugation of 6-amino-6-deoxyluciferin with antibodies can be accomplished by chemical crosslinking methods, such as glutaraldehyde, which react thiol groups on the antibody

• Brand: Biosynth

Chemical properties

• Molecular weight: 279.34 g/mol
• Formula: C₁₁H₉N₃O₂S₂
• Purity: Min. 95%
• Color/Form: Yellow Solid
• InChI: InChI=1S/C11H9N3O2S2/c12-5-1-2-6-8(3-5)18-10(13-6)9-14-7(4-17-9)11(15)16/h1-3,7H,4,12H2,(H,15,16)
• InChI key: InChIKey=HKSJKXOOBAVPKR-UHFFFAOYSA-N
• SMILES: Nc1ccc2nc(C3=NC(C(=O)O)CS3)sc2c1