7-Amino-3-(hydroxymethyl)-cephem-4-carboxylic acid

CAS: 15690-38-7

Ref. 3D-FA36388

Product Information

• Name: 7-Amino-3-(hydroxymethyl)-cephem-4-carboxylic acid
• Synonyms: (6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-Amino-3-hydroxymethylceph-3-em-4-carboxylic acid, 3-Hydroxymethyl-7-aminoceph-3-em-4-carboxylic acid, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, (6R-trans)-, 7-Amino-3-(Hydroxymethyl)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid, 7-Amino-3-hydoxymethyl-3-cephem-carboxylic acid, 7-Amino-3-hydroxymethyl-3-cephem-4-carboxylic acid, 7-Amino-deacetylcephalosporanic acid, 7β-Amino-3-(hydroxymethyl)-3-cephem-4-carboxylic acid, Deacetyl-7-aminocephalosporanic acid, Hydroxymethyl-7-Aminocephalosporanic acid

Description

Cefepime is a broad-spectrum antibiotic that belongs to the group of β-lactam antibiotics. It inhibits the growth of bacteria by binding to the 50S ribosomal subunit, which prevents bacterial protein synthesis. Cefepime hydrochloride is a prodrug that is hydrolyzed in vivo to cefepime, its active form. Cefepime hydrochloride has been shown to inhibit the production of subtilisin and acylase, enzymes involved in the digestion of proteins and fats. The hydrolysis reaction also increases the solubility of cefepime. The crystallization process for cefepime hydrochloride involves heating with organic solvents such as methanol and ethanol. This process can be used for purification and isolation from impurities.

• Brand: Biosynth

Chemical properties

• Molecular weight: 230.24 g/mol
• Formula: C₈H₁₀N₂O₄S
• Purity: Min. 95%