3-Amino-6-bromo-2-methoxypyridine

CAS: 89466-18-2

Ref. 3D-FA38696

Product Information

• Name: 3-Amino-6-bromo-2-methoxypyridine
• Synonyms: (6-Bromo-2-methoxypyridin-3-yl)amine, 3-Pyridinamine, 6-bromo-2-methoxy-, 5-Amino-2-bromo-6-methoxypyridine, 6-Bromo-2-Methoxypyridin-3-Amine, 6-Bromo-2-methoxy-3-pyridinamine, 6-Bromo-2-methoxy-pyridin-3-ylamine, 6-Bromo-2-methoxypyridin-3-ylamine, Pyridine, 3-amino-6-bromo-2-methoxy-

Description

3-Amino-6-bromo-2-methoxypyridine is a small molecule inhibitor of serine proteases. It has been shown to inhibit the activity of chymotrypsin, trypsin and cathepsin B by forming covalent bonds with the active site serine residues in these enzymes. The binding of 3-Amino-6-bromo-2-methoxypyridine to the enzyme's active site is aided by its nucleophilic nature. This compound also inhibits the proteolytic activity of papain, which is not inhibited by serine protease inhibitors. 3-Amino-6-bromo-2-methoxypyridine has been shown to have no effect on other proteases such as cysteine and aspartic acid proteases.

• Brand: Biosynth

Chemical properties

• Molecular weight: 203.04 g/mol
• Formula: C₆H₇BrN₂O
• Purity: Min. 95%
• InChI: InChI=1S/C6H7BrN2O/c1-10-6-4(8)2-3-5(7)9-6/h2-3H,8H2,1H3
• InChI key: InChIKey=HSVYYOLSYNEVSP-UHFFFAOYSA-N
• SMILES: COc1nc(Br)ccc1N