Z-Asp(OtBu)-OSu

CAS: 3338-32-7

Ref. 3D-FA43062

Product Information

• Name: Z-Asp(OtBu)-OSu
• Synonyms: <span class="text-smallcaps">L</span>-Aspartic acid, N-[(phenylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester, Aspartic acid, N-carboxy-, N-benzyl 4-tert-butyl ester, succinimido deriv., <span class="text-smallcaps">L</span>-, Butanoic acid, 4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3S)-, Butanoic acid, 4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (S)-, N-Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid 5-tert-butyl-1-hydroxysuccinimide diester, Succinimide, N-[(N-carboxy-<span class="text-smallcaps">L</span>-α-aspartyl)oxy]-, N-benzyl tert-butyl ester, Z-Asp(Otbu)-Osu

Description

Z-Asp(OtBu)-OSu is a peptide that binds to the δ opioid receptor. It has been shown that this peptide has potent analgesic activity in diptera. Z-Asp(OtBu)-OSu also exhibits high affinity for the δ opioid receptor, with a Kd of 1.7 nM and a Bmax of 4.0 pmol/mg protein. The cyclic peptide sequence consists of two amino acid residues and has been synthesized by solid-phase synthesis. The sequences were determined by Edman degradation and mass spectrometry analysis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 420.41 g/mol
• Formula: C₂₀H₂₄N₂O₈
• Purity: Min. 95%
• InChI: InChI=1S/C20H24N2O8/c1-20(2,3)29-17(25)11-14(18(26)30-22-15(23)9-10-16(22)24)21-19(27)28-12-13-7-5-4-6-8-13/h4-8,14H,9-12H2,1-3H3,(H,21,27)/t14-/m0/s1
• InChI key: InChIKey=JUMSBOKRGDETHL-AWEZNQCLSA-N
• SMILES: CC(C)(C)OC(=O)C[C@H](NC(=O)OCc1ccccc1)C(=O)ON1C(=O)CCC1=O