N-(4-(3-(2-Aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine

CAS: 945595-80-2

Ref. 3D-FA43339

Product Information

• Name: N-(4-(3-(2-Aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine
• Synonyms: N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine, 1-Phthalazinamine, N-[4-[[3-(2-amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-, AMG 900

Description

N-(4-(3-(2-Aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine (ZD1839) is a small molecule that has been researched for its potential to treat cancer. ZD1839 is lipophilic and binds to the blood group antigen, which are found on the surface of cancer cells. It is also able to bind to pluripotent cells and induce the production of monoclonal antibodies. ZD1839 has shown efficacy in treating resistant cancers, such as those of the breast, colon, lung, and prostate. This drug has shown promising pharmacokinetic properties in rats, including high bioavailability and low toxicity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 535.51 g/mol
• Formula: C₂₈H₂₁N₇O₅
• Purity: Min. 95%