Apomorphine

CAS: 58-00-4

Ref. 3D-FA44559

Product Information

• Name: Apomorphine
• Synonyms: (-)-10,11-Dihydroxyaporphine, (6aR)-10,11-dihydroxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium, (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo(de,g)chinolin-10,11-diol, (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol, 4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, (R)-, 4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, (R)- (9CI), 4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, (6aR)-, 6a-beta-Aporphine-10,11-diol, 6abeta-Aporphine-10,11-diol, 6aβ-Aporphine-10,11-diol, Apokyn, Apomorfin, Apomorfina, Apomorphin, Hsdb 3289, Ixense, L-Apomorphine, R-(-)-Apomorphine, Unii-N21Far7B4S
• CAS: 58-00-4

Description

Apomorphine is a chemical compound that can be used as an analytical tool to study the effects of dopamine on physiological processes, and pharmacological agents on pharmacokinetics. It is also used in the treatment of Parkinson's disease. Apomorphine is a potent agonist at dopaminergic receptors in the central nervous system, and has been shown to increase locomotor activity and improve the rotarod test performance in rats. Apomorphine binds to dopamine receptors in the brain, replacing dopamine as it becomes depleted. The drug also blocks reuptake of dopamine by neurons and increases release of dopamine from nerve terminals. Apomorphine has a short half-life of about 2 hours, but may have potential for long-term treatment because its effects can last up to 24 hours.

• Brand: Biosynth

Chemical properties

• Molecular weight: 267.32 g/mol
• Formula: C₁₇H₁₇NO₂
• Purity: Min. 95%
• Color/Form: Powder