L-Aspartic acid 4-tert-butyl ester

CAS: 3057-74-7

Ref. 3D-FA46968

Product Information

• Name: L-Aspartic acid 4-tert-butyl ester
• Synonyms: L-Asp(OtBu)-OH, (2R)-2-ammonio-4-tert-butoxy-4-oxobutanoate, (2S)-2-Amino-4-(tert-butoxy)-4-oxobutanoic acid, (2S)-2-Amino-4-[(2-methylpropan-2-yl)oxy]-4-oxobutanoic acid, (2S)-2-ammonio-4-tert-butoxy-4-oxobutanoate, (S)-2-Amino-4-tert-butoxy-4-oxobutanoic acid, 2-Amino-4-Tert-Butoxy-4-Oxobutanoic Acid (Non-Preferred Name), 4-(1,1-Dimethylethyl) hydrogen <span class="text-smallcaps">L</span>-aspartate, <span class="text-smallcaps">L</span>-Aspartic acid 4-tert-butyl ester, <span class="text-smallcaps">L</span>-Aspartic acid β-tert-butyl ester, <span class="text-smallcaps">L</span>-Aspartic acid, 4-(1,1-dimethylethyl) ester, Aspartic acid β-tert-butyl ester, Aspartic acid, 4-tert-butyl ester, L-Aspartic acid-4-tert-butyl ester, β-tert-Butyl <span class="text-smallcaps">L</span>-aspartate, β-tert-Butyl aspartate, 4-(1,1-Dimethylethyl) hydrogen L-aspartate, L-Aspartic acid, 4-(1,1-dimethylethyl) ester, β-tert-Butyl L-aspartate

Description

L-Aspartic acid 4-tert-butyl ester is a peptidomimetic that inhibits the enzyme glycogen phosphorylase. This compound has been shown to be an effective inhibitor of the enzyme in assays and yields, as well as being a good substrate for the enzyme. L-Aspartic acid 4-tert-butyl ester is synthesized by reacting l-aspartic acid with benzoyloxymethyl chloride and chloroformate. The synthesis of L-aspartic acid 4-tert-butyl ester requires a chlorinated solvent such as chloroform. The reaction requires a base to deprotonate the carboxylic acid moiety, which leads to the formation of an enolate intermediate that reacts with the methyl halide to form the product. L-Aspartic acid 4-tert-butyl ester can also be used for diagnosis and treatment of diseases such as

• Brand: Biosynth

Chemical properties

• Molecular weight: 189.21 g/mol
• Formula: C₈H₁₅NO₄
• Purity: Min. 95%
• InChI: InChI=1S/C8H15NO4/c1-8(2,3)13-6(10)4-5(9)7(11)12/h5H,4,9H2,1-3H3,(H,11,12)/t5-/m0/s1
• InChI key: InChIKey=MXWMFBYWXMXRPD-YFKPBYRVSA-N
• SMILES: CC(C)(C)OC(=O)C[C@H](N)C(=O)O