Z-α-aminoisobutyric acid

CAS: 15030-72-5

Ref. 3D-FA48876

Product Information

• Name: Z-α-aminoisobutyric acid
• Synonyms: Z-Aib-OHZ-a-methylalanine, 2-(Cbz-amino)-2-methylpropanoic acid, Z-Aib-OH, CBZ-2-Amino isobutyric acid

Description

Z-alpha-aminoisobutyric acid is an amide with a conformational pattern that resembles the alpha-helix. It has been shown to inhibit the formation of oligomers, which are aggregates of peptides and proteins, in the gas phase. Z-alpha-aminoisobutyric acid also stabilizes peptides and proteins in aqueous solution by preventing them from forming intramolecular hydrogen bonds. The infrared spectroscopy shows that z-alpha-aminoisobutyric acid is a conformer with a dihedral angle of about 120 degrees.

• Brand: Biosynth

Chemical properties

• Molecular weight: 237.25 g/mol
• Formula: C₁₂H₁₅NO₄
• Purity: Min. 95%
• InChI: InChI=1S/C12H15NO4/c1-12(2,10(14)15)13-11(16)17-8-9-6-4-3-5-7-9/h3-7H,8H2,1-2H3,(H,13,16)(H,14,15)
• InChI key: InChIKey=QKVCSJBBYNYZNM-UHFFFAOYSA-N
• SMILES: CC(C)(NC(=O)OCc1ccccc1)C(=O)O