4-Amino-2-methylbenzoic acid

CAS: 2486-75-1

Ref. 3D-FA50958

Product Information

• Name: 4-Amino-2-methylbenzoic acid
• Synonyms: 2-Methyl-p-aminobenzoic acid, 4-Amino-2-Methyl-Benzoic Acid, Benzoic acid, 4-amino-2-methyl-, NSC 49299, o-Toluic acid, 4-amino-
• CAS: 2486-75-1

Description

4-Amino-2-methylbenzoic acid is a low molecular weight compound that has been shown to inhibit the neuraminidase enzyme. It interacts with the imine group of the enzyme and forms a covalent bond, which prevents the release of sialic acid from the terminal sugar residue of glycoproteins. The inhibition of this enzyme leads to decreased bacterial growth. 4-Amino-2-methylbenzoic acid has been shown to be active against Gram positive bacteria such as Staphylococcus aureus and Streptococcus pneumoniae, but not against Gram negative bacteria such as Escherichia coli or Pseudomonas aeruginosa. This compound is also able to inhibit the synthesis of c-reactive protein (CRP) in human erythrocytes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 151.16 g/mol
• Formula: C₈H₉NO₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C8H9NO2/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4H,9H2,1H3,(H,10,11)
• InChI key: InChIKey=XRSQZFJLEPBPOZ-UHFFFAOYSA-N
• SMILES: Cc1cc(N)ccc1C(=O)O