5-Acetylindole

CAS: 53330-94-2

Ref. 3D-FA52333

Product Information

• Name: 5-Acetylindole
• Synonyms: 1-(1H-Indol-5-yl)ethanone5-Indolyl-methylketone, 1-(1H-Indol-5-yl)ethan-1-one, 1-(1H-Indol-5-yl)ethanone, 5-Acetyl-1H-indole, Ethanone, 1-(1H-indol-5-yl)-, Ketone, indol-5-yl methyl
• CAS: 53330-94-2

Description

5-Acetylindole is a synthetic compound that has been shown to have anticancer activity. It inhibits the growth of cancer cells by disrupting their mitochondria, which leads to cell death. 5-Acetylindole was synthesized in an attempt to increase the anticancer efficacy of indole compounds and acetylation of indole rings was found to be an effective strategy for this purpose. Acetylation of the 5 position on the indole ring leads to a more potent antiproliferative agent with decreased potential for resistance development. This compound has been shown to disrupt cellular function in k562 cells, leading to cell death.

• Brand: Biosynth

Chemical properties

• Molecular weight: 159.18 g/mol
• Formula: C₁₀H₉NO
• Purity: Min. 95%
• InChI: InChI=1S/C10H9NO/c1-7(12)8-2-3-10-9(6-8)4-5-11-10/h2-6,11H,1H3
• InChI key: InChIKey=GOFIUEUUROFVMA-UHFFFAOYSA-N
• SMILES: CC(=O)c1ccc2[nH]ccc2c1