3-Aminocrotononitrile
CAS: 1118-61-2
Ref. 3D-FA55469
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Product Information
- 3-Amino-2-butenenitrile
- (2E)-3-aminobut-2-enenitrile
- (2Z)-3-aminobut-2-enenitrile
- 2-Butenenitrile, 3-amino-
- 3-Amino-3-methylacrylonitrile
- 3-Aminobut-2-Enenitrile
- 3-Aminocrotonitrile
- 3-Aminocrotononitrile, (Diacetonitrile
- 3-Iminobutyronitrile)
- Crotononitrile, 3-amino-
- See more synonyms
- Diacetonitrile~3-Iminobutyronitrile
- NSC 102759
- β-Aminocrotonitrile
- β-Aminocrotononitrile
3-Aminocrotononitrile is a synthetic chemotherapeutic agent that inhibits the growth of cancer cells. It prevents the synthesis of DNA, RNA and proteins. 3-Aminocrotononitrile binds to the active methylene group on the DNA molecule, blocking DNA synthesis and preventing replication. It also inhibits protein synthesis by binding to the amino groups on ribosomes. 3-Aminocrotononitrile is metabolized into an enolate anion, which reacts with chloride ions to form a diacetonitrile linkage between two nitrogen atoms of the compound. This reaction produces ethylene diamine as a byproduct.
Chemical properties
Technical inquiry about: 3D-FA55469 3-Aminocrotononitrile
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