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2-Amino-4-methylbenzonitrile
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2-Amino-4-methylbenzonitrile

CAS: 26830-96-6

Ref. 3D-FA70616

25g
152.00 €
50g
216.00 €
100g
339.00 €
250g
601.00 €
500g
917.00 €
Estimated delivery in United States, on Friday 24 May 2024

Product Information

Name:
2-Amino-4-methylbenzonitrile
Synonyms:
  • 2-Amino-p-toluonitrile
  • 2-Cyano-5-methylaniline
  • 4-Methyl-2-aminobenzonitrile
  • 4-Methylanthranilonitrile
  • Benzonitrile, 2-amino-4-methyl-
  • p-Tolunitrile, 2-amino-
Description:

2-Amino-4-methylbenzonitrile is a potent anticancer drug that inhibits the growth of cancer cells by targeting the active site of DNA polymerase β. It has been shown to have potent cytotoxicity against colorectal adenocarcinoma cells and cervical cancer cells, as well as inhibit cell proliferation and induce apoptosis in a number of other cancers. 2-Amino-4-methylbenzonitrile has been shown to be effective in nanomolar concentrations, which is important for potential use in combination therapies. This drug has also been studied using a variety of molecular profiling techniques to identify its mechanism of action. 2-Amino-4-methylbenzonitrile has been found to bind to the active site on DNA polymerase β and inhibit its activity, leading to the accumulation of errors during replication. This accumulation leads to the inhibition of protein synthesis and cell division, causing apoptosis.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
132.16 g/mol
Formula:
C8H8N2
Purity:
Min. 95%
Color/Form:
Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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