2-Amino-5,6-dimethylbenzothiazole

CAS: 29927-08-0

Ref. 3D-FA75856

Product Information

• Name: 2-Amino-5,6-dimethylbenzothiazole
• Synonyms: (5,6-Dimethylbenzothiazol-2-yl)amine, 2-Amino-5,6-dimethyl-1,3-benzothiazol, 2-Amino-5,6-dimethyl-1,3-benzothiazole, 2-Benzothiazolamine, 5,6-Dimethyl-, 5,6-Dimethyl-1,3-Benzothiazol-2-Amine, 5,6-Dimethyl-1,3-benzothiazol-2-ylamine, 5,6-Dimethyl-2-aminobenzothiazole, 5,6-Dimethyl-2-benzothiazolamine, 5,6-Dimethylbenzo[d]thiazol-2-amine, 5,6-Dimethylbenzothiazol-2-Ylamine, Benzothiazole, 2-amino-5,6-dimethyl-, NSC 140729, Ska 48
• CAS: 29927-08-0

Description

2-Amino-5,6-dimethylbenzothiazole is a reactive compound that binds to acetylcholinesterase. It is used in posttreatment studies as an amine to inhibit the activity of acetylcholinesterase. This agent also has been shown to induce toxicity in melanogaster and other animals, but not humans. 2-Amino-5,6-dimethylbenzothiazole has been shown to have neurotoxicity in African green monkey and rat brains. Neurodegenerative diseases such as Alzheimer's disease are thought to be caused by the accumulation of quinones, which are reactive oxygen species that can cause oxidative damage to cells. The neurotoxicity of 2-Amino-5,6-dimethylbenzothiazole may be due to its ability to induce oxidative stress by producing quinones.

• Brand: Biosynth

Chemical properties

• Molecular weight: 178.26 g/mol
• Formula: C₉H₁₀N₂S
• Purity: Min. 95%
• InChI: InChI=1S/C9H10N2S/c1-5-3-7-8(4-6(5)2)12-9(10)11-7/h3-4H,1-2H3,(H2,10,11)
• InChI key: InChIKey=IODWHFFPQHUDAG-UHFFFAOYSA-N
• SMILES: Cc1cc2nc(N)sc2cc1C