3-Acetyl-2-(aminosulfonyl)-5-chlorothiophene

CAS: 160982-10-5

Ref. 3D-FA75881

Product Information

• Name: 3-Acetyl-2-(aminosulfonyl)-5-chlorothiophene
• Synonyms: 2-Thiophenesulfonamide, 3-Acetyl-5-Chloro-, 3-Acetyl-5-chloro-2-thiophenesulfonamide
• CAS: 160982-10-5

Description

3-Acetyl-2-(aminosulfonyl)-5-chlorothiophene is a ketone that was synthesized to inhibit the enzyme carbonic anhydrase. 3-Acetyl-2-(aminosulfonyl)-5-chlorothiophene has been shown to be enantioselective, which means it is more active against one form of the enzyme than another. It is also brominated and has a thioether group. This compound inhibits carbonic anhydrase by binding to the active site of the enzyme, preventing the formation of carbonic acid from bicarbonate and hydrogen ions. 3-Acetyl-2-(aminosulfonyl)-5-chlorothiophene has been shown in research studies to be a chloride ionizable and hydroxylamine alkylation inhibitor. It also has bromohydrin and tosylation properties, as well as anti-inflammatory activities.

• Brand: Biosynth

Chemical properties

• Molecular weight: 239.7 g/mol
• Formula: C₆H₆ClNO₃S₂
• Purity: Min. 95%
• InChI: InChI=1S/C6H6ClNO3S2/c1-3(9)4-2-5(7)12-6(4)13(8,10)11/h2H,1H3,(H2,8,10,11)
• InChI key: InChIKey=ODLFFSHLXVZFPY-UHFFFAOYSA-N
• SMILES: CC(=O)c1cc(Cl)sc1S(N)(=O)=O