2-Amino-3-(5-Fluoro-1H-Indol-3-Yl)Propanoic Acid

CAS: 343-91-9

Ref. 3D-FA90838

Product Information

• Name: 2-Amino-3-(5-Fluoro-1H-Indol-3-Yl)Propanoic Acid
• Synonyms: 2-Amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid, 5-Fluoro-<span class="text-smallcaps">DL</span>-tryptophan, 5-Fluoro-DL-tryptophan, 5-Fluorotryptophan, <span class="text-smallcaps">DL</span>-5-Fluorotryptophan, <span class="text-smallcaps">DL</span>-Tryptophan, 5-fluoro-, DL-5-Fluorotryptophan, DL-Tryptophan,5-fluoro-, Nsc 9363, Tryptophan, 5-fluoro-, <span class="text-smallcaps">DL</span>-, Tryptophan, 5-fluoro-, DL- (8CI), Tryptophan, 5-fluoro-, Tryptophan, 5-fluoro-, DL-

Description

2-Amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid is a molecule that has been found to have antibacterial activity, which can be due to its steric interactions with the bacterial cell membrane. It also has an effect on wild type and resistant mutants of E. coli and Salmonella, but not on other Gram negative bacteria. The molecule has been found to bind to tryptophan residues in proteins, which may be responsible for its inhibition of protein synthesis. 2-Amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid is a keto acid and it can be synthesized by the enzyme tryptophanyl tRNA synthetase from tryptophan.
2AAAP is a white crystalline solid that melts at 114°C with decomposition. It has been shown to have antiinflammatory properties in animal studies, although

• Brand: Biosynth

Chemical properties

• Molecular weight: 222.22 g/mol
• Formula: C₁₁H₁₁FN₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C11H11FN2O2/c12-7-1-2-10-8(4-7)6(5-14-10)3-9(13)11(15)16/h1-2,4-5,9,14H,3,13H2,(H,15,16)
• InChI key: InChIKey=INPQIVHQSQUEAJ-UHFFFAOYSA-N
• SMILES: NC(Cc1c[nH]c2ccc(F)cc12)C(=O)O