alpha-(Aminomethyl)-3-(Trifluoromethyl)-Benzenemethanol
CAS: 21172-28-1
Ref. 3D-FA94295
| 50mg | To inquire | |
| 100mg | To inquire | |
| 250mg | To inquire |
Product Information
- 2-Amino-1-[3-(trifluormethyl)phenyl]ethanol
- 2-Amino-1-[3-(trifluoromethyl)phenyl]ethan-1-ol
- 2-Hydroxy-2-[(3-trifluoromethyl)phenyl]ethanamine
- Benzenemethanol, Alpha-(Aminomethyl)-3-(Trifluoromethyl)-
- Benzenemethanol, α-(aminomethyl)-3-(trifluoromethyl)-
- Benzyl alcohol, α-(aminomethyl)-m-(trifluoromethyl)-
- α-(Aminomethyl)-3-(trifluoromethyl)benzenemethanol
Alpha-Aminomethyl-3-(trifluoromethyl)benzenemethanol (AMTB) is a potent inhibitor of the enzyme S-adenosyl-L-methionine synthetase. It is used in medicinal chemistry to study the conformational and kinetic properties of this enzyme. AMTB binds to the catalytic site of S-adenosyl-L-methionine synthetase, thereby blocking the production of a key metabolite and consequently inhibiting DNA synthesis. This compound has been shown to have anticancer activity in vitro by inhibiting protein synthesis. X-ray crystallography studies have revealed that AMTB binds to the active site of the enzyme with high affinity, occupying space that would otherwise be occupied by ATP.
Chemical properties
Technical inquiry about: 3D-FA94295 alpha-(Aminomethyl)-3-(Trifluoromethyl)-Benzenemethanol
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