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[(2R,3R,5R)-5-(6-Aminopurin-9-Yl)-3-Fluorooxolan-2-Yl]Methanol
CAS: 110143-09-4
Ref. 3D-FA96947
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Product Information
- 2',3'-Dideoxy-2'-fluoro-ara-A
- 2',3'-Dideoxy-2'-fluoro-beta-D-arabinofuranosyladenine
- 2',3'-Dideoxy-3'-Fluoroadenosine
- 2'-Fluoro-2',3'-dideoxyarabinosyl adenine
- 9-(2,3-Dideoxy-3-fluoro-β-<span class="text-smallcaps">D</span>-threo-pentofuranosyl)-9H-purin-6-amine
- 9H-Purin-6-amine, 9-(2,3-dideoxy-3-fluoro-beta-D-threo-pentofuranosyl)-
- 9H-Purin-6-amine, 9-(2,3-dideoxy-3-fluoro-β-<span class="text-smallcaps">D</span>-threo-pentofuranosyl)-
- Ddf-ara-A
[(2R,3R,5R)-5-(6-Aminopurin-9-Yl)-3-Fluorooxolan-2-Yl]Methanol is an immunosuppressive agent that belongs to the class of carbocyclic purines. It is a prodrug that is metabolized to 6-aminopurine (6AP), which suppresses the immune system by interfering with the synthesis of DNA and RNA in T cells and B cells. The effective dose for humans has been shown to be 0.4 mg/kg/day for 2 weeks. [(2R,3R,5R)-5-(6-Aminopurin-9-Yl)-3-Fluorooxolan-2-Yl]Methanol has been shown to inhibit cellular proliferation in human lymphocytes. This drug is not active against viruses or other cytopathogens.
Chemical properties
Technical inquiry about: 3D-FA96947 [(2R,3R,5R)-5-(6-Aminopurin-9-Yl)-3-Fluorooxolan-2-Yl]Methanol
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