[(2S,4R,5R)-5-(6-Aminopurin-9-Yl)-4-Fluorooxolan-2-Yl]Methanol

CAS: 110143-05-0

Ref. 3D-FA96948

Product Information

• Name: [(2S,4R,5R)-5-(6-Aminopurin-9-Yl)-4-Fluorooxolan-2-Yl]Methanol
• Synonyms: 2',3'-Dideoxy-2'-fluoroadenosine, 2′,3′-Dideoxy-2′-fluoroadenosine, 2′-Fluoro-2′,3′-dideoxyadenosine, Adenosine, 2',3'-dideoxy-2'-fluoro-, Adenosine, 2′,3′-dideoxy-2′-fluoro-

Description

[(2S,4R,5R)-5-(6-Aminopurin-9-Yl)-4-Fluorooxolan-2-Yl]Methanol is an analog of the drug zidovudine (AZT) that has been shown to be active against HIV. It has a bicyclic heterocycle with a pyrrolo[2,3-d]pyrimidine ring and is used as an antimicrobial agent. [(2S,4R,5R)-5-(6-Aminopurin-9-Yl)-4-Fluorooxolan-2-Yl]Methanol binds to the lymphocyte receptor and inhibits viral replication by inhibiting DNA polymerase activity. This drug also has antiinflammatory properties in tissue culture and in rats with bowel disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 253.23 g/mol
• Formula: C₁₀H₁₂FN₅O₂
• Purity: Min. 95%
• InChI: InChI=1S/C10H12FN5O2/c11-6-1-5(2-17)18-10(6)16-4-15-7-8(12)13-3-14-9(7)16/h3-6,10,17H,1-2H2,(H2,12,13,14)/t5-,6+,10+/m0/s1
• InChI key: InChIKey=KBEMFSMODRNJHE-BAJZRUMYSA-N
• SMILES: Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)C[C@H]1F