(5-Amino-1,3-Dimethyl-1H-Pyrazol-4-Yl)(2-Fluorophenyl)Methanone
CAS: 31272-21-6
Ref. 3D-FA97193
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Product Information
- methanone, (5-amino-1,3-dimethyl-1H-pyrazol-4-yl)(2-fluorophenyl)-
L-685,458 is a pyrazole analog that binds to the amide site of the dopamine receptor and inhibits its activity. The cytosolic binding affinity of L-685,458 has been shown in vitro with purified rat brain cytosol. L-685,458 also binds to DNA with detectable activity and has been shown to inhibit serum prolactin levels in rats. It also inhibits dopamine uptake into plant cells at concentrations that are not cytotoxic for the cells. L-685,458 was found to have no effect on striatal dopamine concentrations in mice that were injected with this drug. This drug is toxic to animals and should not be used in humans.>
Chemical properties
Technical inquiry about: 3D-FA97193 (5-Amino-1,3-Dimethyl-1H-Pyrazol-4-Yl)(2-Fluorophenyl)Methanone
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