(2S)-2-Amino-3-[6-(Difluoromethyl)-1H-Indol-3-Yl]Propanoic Acid

CAS: 131490-35-2

Ref. 3D-FA97278

Product Information

• Name: (2S)-2-Amino-3-[6-(Difluoromethyl)-1H-Indol-3-Yl]Propanoic Acid
• Synonyms: 6-DF-Trp, 6-(difluoromethyl)-L-tryptophan

Description

(2S)-2-Amino-3-[6-(Difluoromethyl)-1H-Indol-3-Yl]Propanoic Acid is a bifunctional enzyme that catalyzes the conversion of tryptophan to indoleacetic acid. It is a substrate analog that can be converted to its active form by protonation and stabilization. (2S)-2-Amino-3-[6-(Difluoromethyl)-1H-Indol-3-Yl]Propanoic Acid is an acidic compound that reacts with a base to form the neutral form. Fluorine plays an important role in the mechanism of this enzyme, as it stabilizes the negative charge on the nitrogen atom. The chromatographic properties of this compound allow for separation and identification through gas chromatography or liquid chromatography.

• Brand: Biosynth

Chemical properties

• Molecular weight: 254.23 g/mol
• Formula: C₁₂H₁₂F₂N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C12H12F2N2O2/c13-11(14)6-1-2-8-7(3-9(15)12(17)18)5-16-10(8)4-6/h1-2,4-5,9,11,16H,3,15H2,(H,17,18)/t9-/m0/s1
• InChI key: InChIKey=QKEFAXHAMIYOLM-VIFPVBQESA-N
• SMILES: N[C@@H](Cc1c[nH]c2cc(C(F)F)ccc12)C(=O)O