![[1-(6-Aminopurin-9-Yl)-3-Fluoropropan-2-Yl]Oxymethylphosphonic Acid](https://static.cymitquimica.com/products/3D/img/FA98335.png "Click to enlarge")
[1-(6-Aminopurin-9-Yl)-3-Fluoropropan-2-Yl]Oxymethylphosphonic Acid
CAS: 135295-27-1
Ref. 3D-FA98335
| Undefined size | Discontinued |
Product Information
Name:
[1-(6-Aminopurin-9-Yl)-3-Fluoropropan-2-Yl]Oxymethylphosphonic Acid
Synonyms:
- 3-Fpmpa
- Phosphonic acid, ((2-(6-amino-9H-purin-9-yl)-1-(fluoromethyl)ethoxy)methyl)-, (+-)-
- ({[1-(6-amino-9H-purin-9-yl)-3-fluoropropan-2-yl]oxy}methyl)phosphonic acid
Description:
[1-(6-Aminopurin-9-Yl)-3-Fluoropropan-2-Yl]Oxymethylphosphonic Acid is an acyclic nucleoside phosphonate analog that inhibits the RNA transcriptase activity of human pathogens. It binds to the enzyme and prevents the formation of a new strand of RNA, thereby halting the replication process. This nucleotide analog has been shown to be active against viruses such as herpes simplex virus and HIV, as well as against bacteria such as hepatitis B and murine sarcoma virus. It is also active against some protozoa such as Leishmania donovani. [1-(6-Aminopurin-9-Yl)-3-Fluoropropan-2-Yl]Oxymethylphosphonic Acid has also been shown to inhibit Toll Like Receptor 3 (TLR3) signaling, which may contribute to its antiv
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
305.2 g/mol
Formula:
C9H13FN5O4P
Purity:
Min. 95%
InChI:
InChI=1S/C9H13FN5O4P/c10-1-6(19-5-20(16,17)18)2-15-4-14-7-8(11)12-3-13-9(7)15/h3-4,6H,1-2,5H2,(H2,11,12,13)(H2,16,17,18)
InChI key:
InChIKey=BFZJTDBFUROXJA-UHFFFAOYSA-N
SMILES:
Nc1ncnc2c1ncn2CC(CF)OCP(=O)(O)O
MDL:
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