13,14-Dihydro-15-keto prostaglandin E1

CAS: 5094-14-4

Ref. 3D-FAA09414

Product Information

• Name: 13,14-Dihydro-15-keto prostaglandin E1
• Synonyms: (11α)-11-Hydroxy-9,15-dioxoprostan-1-oic acid, 11α-Hydroxy-9,15-diketoprostanoic acid, 11α-Hydroxy-9,15-dioxoprostanoic acid, 13,14-Dihydro-15-keto-PGE₁, 13,14-Dihydro-15-ketoprostaglandin E₁, 13,14-Dihydro-15-oxo-PGE₁, 15-Oxodihydroprostaglandin E₁, 15-keto-13,14-Dihydro-PGE₁, 15-keto-13,14-Dihydroprostaglandin E₁, Cyclopentaneheptanoic acid, 3-hydroxy-5-oxo-2-(3-oxooctyl)-, Cyclopentaneheptanoic acid, 3-hydroxy-5-oxo-2-(3-oxooctyl)-, stereoisomer, Dihydro-15-ketoprostaglandin E₁, Prostan-1-oic acid, 11-hydroxy-9,15-dioxo-, (11alpha)-, Prostan-1-oic acid, 11-hydroxy-9,15-dioxo-, (11α)-, U 21002

Description

13,14-Dihydro-15-keto prostaglandin E1 is a metabolite of prostaglandin E1. It is formed by the action of the enzyme, 15-hydroxyprostaglandin dehydrogenase, on prostaglandin E1. 13,14-Dihydro-15-keto prostaglandin E1 binds to plasma proteins and has a terminal half life of about 2 hours. The drug is inactivated by reaction with plasma proteins and other substances present in the blood and tissues. In vitro studies have shown that it inhibits perfusion through human liver slices. 13,14-dihydro-15-keto prostaglandin E1 has been shown to inhibit platelet aggregation when administered intravenously at pharmacokinetic concentrations of 10 nanomolar or greater. This effect may be due to its ability to bind to platelets through the function of cyclooxygenase (COX

• Brand: Biosynth

Chemical properties

• Molecular weight: 354.48 g/mol
• Formula: C₂₀H₃₄O₅
• Purity: Min. 95%