Product Information
- 11-Azatricyclo(6.2.1.0(2,7))undec-2,4,6-triene
- 11-Azatricyclo[6.2.1.02,7]Undeca-2,4,6-Triene
- Naphthalen-1,4-Imine, 1,2,3,4-Tetrahydro-
1,2,3,4-Tetrahydro-naphthalen-1,4-imine is a protease inhibitor that belongs to the pyrrole class of compounds. It has been shown to inhibit the activity of proteases like chymotrypsin and elastase by binding to their active site. This inhibition prevents hydrolysis of protein substrates and prevents them from being degraded. The compound was optimized for use as a protease inhibitor by incorporating hydrophobic moieties and ionic groups into its structure. The conformational flexibility in its structure also makes it an efficient catalyst for reactions involving benzyne intermediates. 1,2,3,4-Tetrahydro-naphthalen-1,4-imine is activated at the linker level by aspartic acid residues in its active site. This activation aids in catalysis by stabilizing the transition state of substrate molecules with respect to the transition state of
Chemical properties
Technical inquiry about: 3D-FAA17630 1,2,3,4-Tetrahydro-naphthalen-1,4-imine
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