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4-Chlorophenylbiguanide
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4-Chlorophenylbiguanide

CAS: 5304-59-6

Ref. 3D-FAA30459

1gDiscontinued
5gDiscontinued
100mgDiscontinued
250mgDiscontinued
500mgDiscontinued

Discontinued product. For inquiries about similar products, please fill out our form or email us at .


Product Information

Name:
4-Chlorophenylbiguanide
Synonyms:
  • (4-Chlorophenyl)biguanide
  • (p-Chlorophenyl)biguanide
  • 1-(p-Chlorophenyl)biguanide
  • 1-(p-Chlorophenyl)diguanide
  • 2-(4-Chlorophenyl)-1-(diaminomethylidene)guanidine
  • Ai3-52174
  • Biguanide, 1-(p-chlorophenyl)-
  • Imidodicarbonimidic diamide, N-(4-chlorophenyl)-
  • N-(4-Chlorophenyl)imidodicarbonimidic diamide
  • N<sup>1</sup>-(p-Chlorophenyl)biguanide
  • See more synonyms
  • Nsc 220325
Description:

4-Chlorophenylbiguanide is a drug that inhibits the enzyme dihydrofolate reductase, which is involved in the synthesis of DNA. It has been shown to be effective in treating malaria caused by Plasmodium falciparum. The pharmacokinetic properties of 4-chlorophenylbiguanide have been studied in humans and found to be similar in both men and women. The kinetic data for 4-chlorophenylbiguanide in urine samples from healthy volunteers have also been determined. This study showed that it was metabolized by hepatic cytochrome P450 enzymes and rapidly excreted into the urine. The enzyme activities for these enzymes were found to be dose-dependent, with an increase of plasma concentrations following administration of higher doses. Chlorhexidine, a disinfectant used in mouthwashes and surgical scrubs, has been shown to potentiate the inhibitory effect of 4-chlorophenylbiguanide on the

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
211.65 g/mol
Formula:
C8H10ClN5
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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