3-Methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS: 5399-44-0
Ref. 3D-FAA39944
1g | Discontinued | ||
5g | Discontinued | ||
100mg | Discontinued | ||
250mg | Discontinued | ||
500mg | Discontinued | ||
2500mg | Discontinued |
Product Information
3-Methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an inhibitor of the PI3K enzyme that inhibits the phosphoinositide 3 kinase (PI3K) and its downstream products. It has been shown to inhibit proliferation and induce apoptosis in b cell malignancies. This compound also reduces myelofibrosis in mice by inhibiting B cell differentiation. The mechanism of action may be related to the inhibition of PI3Kδ, which is a regulatory subunit of PI3K.