Ethyl 4-Amino-2-methylpyrimidine-5-carboxylate
CAS: 5472-46-8
Ref. 3D-FAA47246
| 1g | 727.00 € | ||
| 100mg | 185.00 € |
Product Information
- 5-Pyrimidinecarboxylic Acid, 4-Amino-2-Methyl-, Ethyl Ester
- Ethyl 4-amino-2-methylpyrimidine-5-carboxylate
Ethyl 4-amino-2-methylpyrimidine-5-carboxylate is a synthetic, nonsteroidal androgen receptor antagonist. It binds to the androgen receptor in prostate cancer cells, which inhibits the function of this receptor and prevents testosterone from activating it. This drug has been shown to have anticancer activity in human lung cancer and human prostate cancer, as well as other cancers. Ethyl 4-amino-2-methylpyrimidine-5-carboxylate is also able to cross the blood brain barrier and inhibit tumor growth in the brain. Human lung tumors are sensitive to this drug at concentrations of 10 μM or higher. The mechanism of action for this drug involves binding to the DNA in tumor cells, inhibiting transcription of genes that regulate cell growth and proliferation. Ethyl 4-amino-2-methylpyrimidine-5 carboxylate has been shown to be effective against tautomeric forms of benzene including
Chemical properties
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