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BIBX 1382
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BIBX 1382

CAS: 196612-93-8

Ref. 3D-FB102671

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Estimated delivery in United States, on Monday 30 Dec 2024

Product Information

Name:
BIBX 1382
Synonyms:
  • Falnidamol
  • Bibx-1382
  • Bibx-1382Bs
  • N8-(3-Chloro-4-fluorophenyl)-N2-(1-methyl-4-piperidinyl)pyrimido[5,4-d]pyrimidine-2,8-diamine
  • N~8~-(3-chloro-4-fluorophenyl)-N~2~-(1-methylpiperidin-4-yl)pyrimido[5,4-d]pyrimidine-2,8-diamine
Description:

BIBX 1382 is a potent inhibitor of the epidermal growth factor receptor (EGFR) and has been shown to be active against solid tumours in cell culture. BIBX 1382 binds to the ATP-binding pocket of the EGFR kinase domain and inhibits the activation of this domain. This inhibition prevents the phosphorylation of downstream proteins, such as tyrosine kinases, which are required for cellular proliferation. BIBX 1382 has low bioavailability due to its poor solubility in water and a high degree of protein binding.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
387.84 g/mol
Formula:
C18H19ClFN7
Purity:
Min. 95%
MDL:
Melting point:
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Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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