3-Bromo-2-hydroxypyridine

CAS: 13466-43-8

Ref. 3D-FB10496

Product Information

• Name: 3-Bromo-2-hydroxypyridine
• Synonyms: 2(1H)-Pyridinone, 3-bromo-, 2(1H)-Pyridone, 3-bromo-, 2-Hydroxy-3-Bromopyridine, 3-Bromo-1,2-dihydropyridin-2-one, 3-Bromo-1H-pyridin-2-one, 3-Bromo-2(1H)-Pyridinone, 3-Bromo-2(1H)-pyridone, 3-Bromo-2-Hydroxypyridine99%, 3-Bromo-2-Pyridinol, 3-Bromo-2-Pyridone, 3-Bromo-2-oxo-1,2-dihydropyridine, 3-Bromo-2-pyridinone, 3-Bromo-Pyridin-2-Ol, 3-Bromopyridin-2-ol, 3-bromopyridin-2(1H)-one, Iflab-Bb F1371-0174
• CAS: 13466-43-8

Description

3-Bromo-2-hydroxypyridine is a low potency competitive inhibitor of the HIV protease that binds to the active site of the enzyme. It has been shown to have anti-cancer activity in prostate cancer cells and also inhibits inflammatory bowel disease by inhibiting serine proteases. 3-Bromo-2-hydroxypyridine is synthesized by reacting 1,2,4-triazole with bromine in the presence of hydrochloric acid. This reaction produces a mixture of substituted pyridines, which are purified using column chromatography. The chemical structure is characterized using NMR spectroscopy and mass spectroscopy.

• Brand: Biosynth

Chemical properties

• Molecular weight: 174 g/mol
• Formula: C₅H₄BrNO
• Purity: Min. 95%