5-Bromo-2-chloro-3-nitropyridine
CAS: 67443-38-3
Ref. 3D-FB10581
| 25g | 136.00 € | ||
| 50g | 192.00 € | ||
| 100g | 325.00 € | ||
| 250g | 633.00 € | ||
| 500g | 1,033.00 € |
Product Information
- 2-Pyridinecarboxylic Acid, 5-Bromo-
- 5-Bromo-2-Carboxypyridine
- 5-Bromo-2-Picolinic Acid
- Iflab-Bb F1957-0001
- Rarechem Al Bo 2390
5-Bromo-2-chloro-3-nitropyridine is a chemical compound that has been shown to have anticancer activity. It has been found to inhibit the phosphoinositide 3 kinase (PI3K) and the mammalian target of rapamycin complex 1 (mTORC1). This drug is also a potent inhibitor of the kinase shp2, which regulates cell proliferation and apoptosis. 5-Bromo-2-chloro-3-nitropyridine inhibits tumor growth in vitro and in vivo. The mechanism of this inhibition may be due to 5-bromo-2,3 nitropyridine's ability to inhibit inflammatory genes such as NFκβ, IL1β, and IL6. 5 - Bromo - 2 - chloro - 3 - nitropyridine has also been shown to inhibit death pathways in cells by inhibiting proapoptotic protein Bax.
Chemical properties
Technical inquiry about: 3D-FB10581 5-Bromo-2-chloro-3-nitropyridine
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