1-Boc-4-pyrazoleboronic acid pinacol ester
CAS: 552846-17-0
Ref. 3D-FB10621
2g | Discontinued | ||
5g | Discontinued | ||
10g | Discontinued | ||
25g | Discontinued | ||
50g | Discontinued |
Product Information
- 1-Boc-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
- 1-tert-Butoxycarbonyl-1H-pyrazole-4-boronic acid pinacol ester
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylic acid tert-butyl ester
- tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate
- Tert-Butyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrazole-1-Carboxylate
1-Boc-4-pyrazoleboronic acid pinacol ester is a novel and innovative compound that has been shown to be an orally active allosteric modulator of the cholinergic M1 receptor. It has been shown to inhibit the release of pro-inflammatory cytokines such as IL-6, IL-8 and TNFα from pancreatic β-cells, which may be due to its ability to induce cell apoptosis. 1-Boc-4-pyrazoleboronic acid pinacol ester is currently in preclinical development for the treatment of type 2 diabetes.