1-Boc-4-pyrazoleboronic acid pinacol ester

CAS: 552846-17-0

Ref. 3D-FB10621

Product Information

• Name: 1-Boc-4-pyrazoleboronic acid pinacol ester
• Synonyms: 1-Boc-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 1-tert-Butoxycarbonyl-1H-pyrazole-4-boronic acid pinacol ester, 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylic acid tert-butyl ester, tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate, Tert-Butyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrazole-1-Carboxylate
• CAS: 552846-17-0

Description

1-Boc-4-pyrazoleboronic acid pinacol ester is a novel and innovative compound that has been shown to be an orally active allosteric modulator of the cholinergic M1 receptor. It has been shown to inhibit the release of pro-inflammatory cytokines such as IL-6, IL-8 and TNFα from pancreatic β-cells, which may be due to its ability to induce cell apoptosis. 1-Boc-4-pyrazoleboronic acid pinacol ester is currently in preclinical development for the treatment of type 2 diabetes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 294.15 g/mol
• Formula: C₁₄H₂₃BN₂O₄
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C14H23BN2O4/c1-12(2,3)19-11(18)17-9-10(8-16-17)15-20-13(4,5)14(6,7)21-15/h8-9H,1-7H3
• InChI key: InChIKey=IPISOFJLWYBCAV-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)cn1